Cancer Companion Guide

Colorectal cancer — once considered a disease of older adults — is now the number one cause of cancer-related death in Americans under age 50 , according to new research published in the Journal of the American Medical Association (JAMA). This alarming shift marks a major public-health milestone and highlights the urgent need for better awareness, early screening, and research into causes.  A Dramatic Shift in Cancer Mortality Trends Until recently, cancers like lung, breast, and leukemia were the top killers for people under 50. But a new analysis of U.S. cancer mortality data from 1990 through 2023 shows that colorectal cancer (CRC) mortality has increased by about 1.1% per year , even as deaths from most major cancers have declined. By 2023, colorectal cancer had risen from the fifth leading cause of cancer death in younger adults to the first . ( American Hospital Association ) Key Trend Drivers Decreases in death rates for other cancers (lung, breast, leukemia, brain). ...

Abstract Cancer remains a leading global cause of death, with incidence and mortality rates expected to rise in coming decades. While therapeutic advances have led to incremental survival gains, the most impactful strategy is prevention through modifiable risk factors. This article synthesizes current high-quality evidence and major guideline recommendations on diet, lifestyle, screenings, environmental exposures, and supplements to optimize cancer prevention strategies for clinicians, writers, and health-minded readers. 1. Introduction Despite trillions spent on cancer research  (The Lancet), cancer still kills around 10 million people a year  (WHO) and is a leading cause of death globally. The incidence of common cancers such as breast, lung, and colon cancer is expected to increase by over 75% between 2022 and 2050.   Credit:  Statista Ladanie et al (JAMA 2020) showed that over the past fifteen years, new therapies have led to an overall survival improvement of...

Abstract Cancer remains a leading cause of mortality worldwide, with incidence rates projected to rise significantly in the coming decades. While advances in treatment have modestly improved survival, prevention through modifiable risk factors remains underemphasized. This review synthesizes current evidence on the role of diet, lifestyle, and dietary supplements in cancer prevention, drawing on systematic reviews, meta-analyses, and major guideline recommendations. The I-PREVENT CANCER protocol is introduced as a practical, evidence-based framework for reducing cancer risk. Introduction Despite trillions spent on cancer research , cancer still kills around 10 million people a year and is a leading cause of death globally. The incidence of common cancers such as breast, lung, and colon cancer is expected to increase by over 75% between 2022 and 2050.  While treatment advances offer incremental improvements in survival, prevention strategies—particularly those related to diet and l...